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Oncolytic Adenovirus Research

Oncolytic adenoviridae are human adenoviruses that have been genetically manipulated in such a way as to allow for replication in tumor cells to destroy the tumor. [...]

What is the Adenovirus?

The Adenovirus or Adenoviridae to put the name into scientific terms, are medium sized icosahedral viruses with 57 different serotypes. A serotype is simply a classification for a series of micro-organisms. It can help to think of serotypes as the “family” of the virus. These serotypes are responsible for between 5-10% of upper respiratory infections in children as well as various other infections in adults. All vertebrates are susceptible to Adenoviruses which were first discovered in human adenoids, from which they derive their name. The Adenovirus in humans can cause upper respiratory disease, conjunctivitis, and gastroenteritis. The Adenovirus’ variants are very common in children and can often cause diarrhea. The virus is much more common in children and infants than adults and can often spread quickly through daycare centers and schools.